Recent publications

  • Dendrou CA, McVean G, Fugger L. 2016. Neuroinflammation - using big data to inform clinical practice. Nat Rev Neurol, 12 (12), pp. 685-698. | Show Abstract | Read more
  • Corbel V, Achee NL, Chandre F, Coulibaly MB, Dusfour I, Fonseca DM, Grieco J, Juntarajumnong W, Lenhart A, Martins AJ et al. 2016. Tracking Insecticide Resistance in Mosquito Vectors of Arboviruses: The Worldwide Insecticide resistance Network (WIN). PLoS Negl Trop Dis, 10 (12), pp. e0005054. | Read more
  • Eberle MA, Fritzilas E, Krusche P, Källberg M, Moore BL, Bekritsky MA, Iqbal Z, Chuang HY, Humphray SJ, Halpern AL et al. 2016. A reference data set of 5.4 million phased human variants validated by genetic inheritance from sequencing a three-generation 17-member pedigree. Genome Res, | Show Abstract | Read more
  • Lakhal-Littleton S, Wolna M, Chung YJ, Christian HC, Heather LC, Brescia M, Ball V, Diaz R, Santos A, Biggs D et al. 2016. An essential cell-autonomous role for hepcidin in cardiac iron homeostasis. Elife, 5 | Show Abstract | Read more
  • Miller KA, Twigg SR, McGowan SJ, Phipps JM, Fenwick AL, Johnson D, Wall SA, Noons P, Rees KE, Tidey EA et al. 2016. Diagnostic value of exome and whole genome sequencing in craniosynostosis. J Med Genet, | Show Abstract | Read more
  • Dorman A, Baer D, Tomlinson I, Mott R, Iraqi FA. 2016. Erratum to: Genetic analysis of intestinal polyp development in Collaborative Cross mice carrying the Apc Min/+ mutation. BMC Genet, 17 (1), pp. 147. | Read more
  • Ried JS, Jeff M J, Chu AY, Bragg-Gresham JL, van Dongen J, Huffman JE, Ahluwalia TS, Cadby G, Eklund N, Eriksson J et al. 2016. A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nat Commun, 7 pp. 13357. | Show Abstract | Read more
  • Glaire MA, Brown M, Church DN, Tomlinson I. 2016. Cancer predisposition syndromes: lessons for truly precision medicine. J Pathol, | Show Abstract | Read more
  • Liu J, Lončar I, Collée JM, Bolla MK, Dennis J, Michailidou K, Wang Q, Andrulis IL, Barile M, Beckmann MW et al. 2016. rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk. Sci Rep, 6 pp. 36874. | Show Abstract | Read more
  • Lotta LA, Gulati P, Day FR, Payne F, Ongen H, van de Bunt M, Gaulton KJ, Eicher JD, Sharp SJ, Luan J et al. 2016. Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance. Nat Genet, | Show Abstract | Read more
  • Bryant JM, Grogono DM, Rodriguez-Rincon D, Everall I, Brown KP, Moreno P, Verma D, Hill E, Drijkoningen J, Gilligan P et al. 2016. Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium. Science, 354 (6313), pp. 751-757. | Show Abstract | Read more
  • Lind L, Ng E, Ingelsson E, Lindgren C, Salihovic S, van Bavel B, Mahajan A, Lampa E, Morris AP, Lind PM. 2017. Genetic and methylation variation in the CYP2B6 gene is related to circulating p,p'-dde levels in a population-based sample. Environ Int, 98 pp. 212-218. | Show Abstract | Read more
  • Srimuang K, Miotto O, Lim P, Fairhurst RM, Kwiatkowski DP, Woodrow CJ, Imwong M, Tracking Resistance to Artemisinin Collaboration. 2016. Analysis of anti-malarial resistance markers in pfmdr1 and pfcrt across Southeast Asia in the Tracking Resistance to Artemisinin Collaboration. Malar J, 15 (1), pp. 541. | Show Abstract | Read more
  • Amato R, Lim P, Miotto O, Amaratunga C, Dek D, Pearson RD, Almagro-Garcia J, Neal AT, Sreng S, Suon S et al. 2016. Genetic markers associated with dihydroartemisinin-piperaquine failure in Plasmodium falciparum malaria in Cambodia: a genotype-phenotype association study. Lancet Infect Dis, | Show Abstract | Read more
  • Dendrou CA, Cortes A, Shipman L, Evans HG, Attfield KE, Jostins L, Barber T, Kaur G, Kuttikkatte SB, Leach OA et al. 2016. Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity. Sci Transl Med, 8 (363), pp. 363ra149. | Show Abstract | Read more
  • Broix L, Jagline H, L Ivanova E, Schmucker S, Drouot N, Clayton-Smith J, Pagnamenta AT, Metcalfe KA, Isidor B, Louvier UW et al. 2016. Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia. Nat Genet, 48 (11), pp. 1349-1358. | Show Abstract | Read more
  • Barban N, Jansen R, de Vlaming R, Vaez A, Mandemakers JJ, Tropf FC, Shen X, Wilson JF, Chasman DI, Nolte IM et al. 2016. Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Nat Genet, 48 (12), pp. 1462-1472. | Show Abstract | Read more
  • Bonifacio E, Mathieu C, Nepom GT, Ziegler AG, Anhalt H, Haller MJ, Harrison LC, Hebrok M, Kushner JA, Norris JM et al. 2017. Rebranding asymptomatic type 1 diabetes: the case for autoimmune beta cell disorder as a pathological and diagnostic entity. Diabetologia, 60 (1), pp. 35-38. | Show Abstract | Read more
  • Vince N, Li H, Ramsuran V, Naranbhai V, Duh FM, Fairfax BP, Saleh B, Knight JC, Anderson SK, Carrington M. 2016. HLA-C Level Is Regulated by a Polymorphic Oct1 Binding Site in the HLA-C Promoter Region. Am J Hum Genet, 99 (6), pp. 1353-1358. | Show Abstract | Read more
  • Hamdi Y, Soucy P, Adoue V, Michailidou K, Canisius S, Lemaçon A, Droit A, Andrulis IL, Anton-Culver H, Arndt V et al. 2016. Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21. Oncotarget, | Show Abstract | Read more
  • Borghese B, Zondervan KT, Abrao MS, Chapron C, Vaiman D. 2016. Recent insights on the genetics and epigenetics of endometriosis. Clin Genet, | Show Abstract | Read more
  • Hodgson SH, Llewellyn D, Silk SE, Milne KH, Elias SC, Miura K, Kamuyu G, Juma EA, Magiri C, Muia A et al. 2016. Changes in Serological Immunology Measures in UK and Kenyan Adults Post-controlled Human Malaria Infection. Front Microbiol, 7 (OCT), pp. 1604. | Show Abstract | Read more
  • Stelloo E, Jansen AM, Osse EM, Nout RA, Creutzberg CL, Ruano D, Church DN, Morreau H, Smit VT, van Wezel T, Bosse T. 2016. Practical guidance for mismatch repair-deficiency testing in endometrial cancer. Ann Oncol, pp. mdw542-mdw542. | Show Abstract | Read more
  • Loley C, Alver M, Assimes TL, Bjonnes A, Goel A, Gustafsson S, Hernesniemi J, Hopewell JC, Kanoni S, Kleber ME et al. 2016. No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis. Sci Rep, 6 pp. 35278. | Show Abstract | Read more
  • Uimari O, Auvinen J, Jokelainen J, Puukka K, Ruokonen A, Järvelin MR, Piltonen T, Keinänen-Kiukaanniemi S, Zondervan K, Järvelä I et al. 2016. Uterine fibroids and cardiovascular risk. Hum Reprod, 31 (12), pp. 2689-2703. | Show Abstract | Read more
  • Muranen TA, Greco D, Blomqvist C, Aittomäki K, Khan S, Hogervorst F, Verhoef S, Pharoah PD, Dunning AM, Shah M et al. 2016. Genetic modifiers of CHEK2*1100delC-associated breast cancer risk. Genet Med, | Show Abstract | Read more
  • Broderick P, Dobbins SE, Chubb D, Kinnersley B, Dunlop MG, Tomlinson I, Houlston RS. 2016. Validation of Recently Proposed Colorectal Cancer Susceptibility Gene Variants in an Analysis of Families and Patients-a Systematic Review. Gastroenterology, | Show Abstract | Read more
  • Dilthey AT, Gourraud PA, Mentzer AJ, Cereb N, Iqbal Z, McVean G. 2016. High-Accuracy HLA Type Inference from Whole-Genome Sequencing Data Using Population Reference Graphs. PLoS Comput Biol, 12 (10), pp. e1005151. | Show Abstract | Read more
  • Pagnamenta AT, Howard MF, Knight SJ, Keays DA, Quaghebeur G, Taylor JC, Kini U. 2016. Activation of an exonic splice-donor site in exon 30 of CDK5RAP2 in a patient with severe microcephaly and pigmentary abnormalities. Clin Case Rep, 4 (10), pp. 952-956. | Show Abstract | Read more
  • Bohorquez M, Sahasrabudhe R, Criollo A, Sanabria-Salas MC, Vélez A, Castro JM, Marquez JR, Mateus G, Bolaños F, Panqueva C et al. 2016. Clinical manifestations of colorectal cancer patients from a large multicenter study in Colombia. Medicine (Baltimore), 95 (40), pp. e4883. | Show Abstract | Read more
  • Thomson E, Ip CLC, Badhan A, Christiansen MT, Adamson W, Ansari MA, Bibby D, Breuer J, Brown A, Bowden R et al. 2016. Comparison of next-generation sequencing technologies for comprehensive assessment of full-length hepatitis C viral genomes Journal of Clinical Microbiology, 54 (10), pp. 2470-2484. | Citations: 1 (Scopus) | Show Abstract
  • Todd JA, Evangelou M, Cutler AJ, Pekalski ML, Walker NM, Stevens HE, Porter L, Smyth DJ, Rainbow DB, Ferreira RC et al. 2016. Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial. PLoS Med, 13 (10), pp. e1002139. | Show Abstract | Read more
  • Horikoshi M, Beaumont RN, Day FR, Warrington NM, Kooijman MN, Fernandez-Tajes J, Feenstra B, van Zuydam NR, Gaulton KJ, Grarup N et al. 2016. Genome-wide associations for birth weight and correlations with adult disease. Nature, 538 (7624), pp. 248-252. | Show Abstract | Read more
  • Kirchhof P, Benussi S, Kotecha D, Ahlsson A, Atar D, Casadei B, Castella M, Diener HC, Heidbuchel H, Hendriks J et al. 2016. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. Eur J Cardiothorac Surg, 50 (5), pp. e1-e88. | Read more
  • Bardella C, Al-Dalahmah O, Krell D, Brazauskas P, Al-Qahtani K, Tomkova M, Adam J, Serres S, Lockstone H, Freeman-Mills L et al. 2016. Expression of Idh1(R132H) in the Murine Subventricular Zone Stem Cell Niche Recapitulates Features of Early Gliomagenesis. Cancer Cell, 30 (4), pp. 578-594. | Show Abstract | Read more
  • Camps C, Petousi N, Bento C, Cario H, Copley RR, McMullin MF, van Wijk R, Ratcliffe PJ, Robbins PA, Taylor JC, WGS500 Consortium. 2016. Gene panel sequencing improves the diagnostic work-up of patients with idiopathic erythrocytosis and identifies new mutations. Haematologica, 101 (11), pp. 1306-1318. | Show Abstract | Read more
  • Kerr RS, Love S, Segelov E, Johnstone E, Falcon B, Hewett P, Weaver A, Church D, Scudder C, Pearson S et al. 2016. Adjuvant capecitabine plus bevacizumab versus capecitabine alone in patients with colorectal cancer (QUASAR 2): an open-label, randomised phase 3 trial. Lancet Oncol, 17 (11), pp. 1543-1557. | Citations: 2 (Scopus) | Show Abstract | Read more
  • Scherag A, Schöneweck F, Kesselmeier M, Taudien S, Platzer M, Felder M, Sponholz C, Rautanen A, Hill AV, Hinds CJ et al. 2016. Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28Day Mortality. EBioMedicine, 12 pp. 239-246. | Citations: 3 (Scopus) | Show Abstract | Read more
  • Hastings R, de Villiers CP, Hooper C, Ormondroyd L, Pagnamenta A, Lise S, Salatino S, Knight SJ, Taylor JC, Thomson KL et al. 2016. Combination of Whole Genome Sequencing, Linkage, and Functional Studies Implicates a Missense Mutation in Titin as a Cause of Autosomal Dominant Cardiomyopathy With Features of Left Ventricular Noncompaction. Circ Cardiovasc Genet, 9 (5), pp. 426-435. | Citations: 1 (Scopus) | Show Abstract | Read more
  • Surendran P, Drenos F, Young R, Warren H, Cook JP, Manning AK, Grarup N, Sim X, Barnes DR, Witkowska K et al. 2016. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nat Genet, 48 (10), pp. 1151-1161. | Citations: 2 (Scopus) | Show Abstract | Read more
  • Popitsch N, WGS500 Consortium, Schuh A, Taylor JC. 2016. ReliableGenome: annotation of genomic regions with high/low variant calling concordance. Bioinformatics, | Show Abstract | Read more
  • Southey MC, Goldgar DE, Winqvist R, Pylkäs K, Couch F, Tischkowitz M, Foulkes WD, Dennis J, Michailidou K, van Rensburg EJ et al. 2016. PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS. J Med Genet, 53 (12), pp. 800-811. | Citations: 1 (Scopus) | Show Abstract | Read more
  • Ghoussaini M, French JD, Michailidou K, Nord S, Beesley J, Canisus S, Hillman KM, Kaufmann S, Sivakumaran H, Moradi Marjaneh M et al. 2016. Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation. Am J Hum Genet, 99 (4), pp. 903-911. | Show Abstract | Read more
  • Lange L, Pagnamenta AT, Lise S, Clasper S, Stewart H, Akha ES, Quaghebeur G, Knight SJ, Keays DA, Taylor JC, Kini U. 2016. A de novo frameshift in HNRNPK causing a Kabuki-like syndrome with nodular heterotopia. Clin Genet, 90 (3), pp. 258-262. | Show Abstract | Read more
  • Rampling T, Ewer KJ, Bowyer G, Bliss CM, Edwards NJ, Wright D, Payne RO, Venkatraman N, de Barra E, Snudden CM et al. 2016. Safety and High Level Efficacy of the Combination Malaria Vaccine Regimen of RTS,S/AS01B With Chimpanzee Adenovirus 63 and Modified Vaccinia Ankara Vectored Vaccines Expressing ME-TRAP. J Infect Dis, 214 (5), pp. 772-781. | Show Abstract | Read more
  • Hore V, Viñuela A, Buil A, Knight J, McCarthy MI, Small K, Marchini J. 2016. Tensor decomposition for multiple-tissue gene expression experiments. Nat Genet, 48 (9), pp. 1094-1100. | Show Abstract | Read more
  • Mahajan A, Rodan AR, Le TH, Gaulton KJ, Haessler J, Stilp AM, Kamatani Y, Zhu G, Sofer T, Puri S et al. 2016. Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity. Am J Hum Genet, 99 (3), pp. 636-646. | Show Abstract | Read more
  • Casadei B, Collins R, Zheng Z. 2016. Perioperative Rosuvastatin in Cardiac Surgery. N Engl J Med, 375 (9), pp. 903. | Read more
  • Calis JC, Phiri KS, Faragher EB, Brabin BJ, Bates I, Cuevas LE, de Haan RJ, Phiri AI, Malange P, Khoka M et al. 2016. Severe anemia in Malawian children. Malawi Med J, 28 (3), pp. 99-107. | Show Abstract
  • van der Laan SW, Fall T, Soumaré A, Teumer A, Sedaghat S, Baumert J, Zabaneh D, van Setten J, Isgum I, Galesloot TE et al. 2016. Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study. J Am Coll Cardiol, 68 (9), pp. 934-945. | Citations: 1 (Scopus) | Show Abstract | Read more
  • Kirchhof P, Benussi S, Kotecha D, Ahlsson A, Atar D, Casadei B, Castella M, Diener HC, Heidbuchel H, Hendriks J et al. 2016. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. Europace, 18 (11), pp. 1609-1678. | Read more
  • Kirchhof P, Benussi S, Kotecha D, Ahlsson A, Atar D, Casadei B, Castella M, Diener HC, Heidbuchel H, Hendriks J et al. 2016. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS: The Task Force for the management of atrial fibrillation of the European Society of Cardiology (ESC)Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESCEndorsed by the European Stroke Organisation (ESO). Eur Heart J, 37 (38), pp. 2893-2962. | Read more
  • Guo Y, Warren Andersen S, Shu XO, Michailidou K, Bolla MK, Wang Q, Garcia-Closas M, Milne RL, Schmidt MK, Chang-Claude J et al. 2016. Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent. PLoS Med, 13 (8), pp. e1002105. | Show Abstract | Read more
  • Thomsen SK, Ceroni A, van de Bunt M, Burrows C, Barrett A, Scharfmann R, Ebner D, McCarthy MI, Gloyn AL. 2016. Systematic Functional Characterization of Candidate Causal Genes for Type 2 Diabetes Risk Variants. Diabetes, 65 (12), pp. 3805-3811. | Show Abstract | Read more
  • Painter JN, O'Mara TA, Marquart L, Webb PM, Attia J, Medland SE, Cheng T, Dennis J, Holliday EG, McEvoy M et al. 2016. Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer. Cancer Epidemiol Biomarkers Prev, 25 (11), pp. 1503-1510. | Show Abstract | Read more
  • McCarthy S, Das S, Kretzschmar W, Delaneau O, Wood AR, Teumer A, Kang HM, Fuchsberger C, Danecek P, Sharp K et al. 2016. A reference panel of 64,976 haplotypes for genotype imputation. Nat Genet, 48 (10), pp. 1279-1283. | Citations: 2 (Scopus) | Show Abstract | Read more
  • Piret SE, Gorvin CM, Trinh A, Taylor J, Lise S, Taylor JC, Ebeling PR, Thakker RV. 2016. Autosomal dominant osteopetrosis associated with renal tubular acidosis is due to a CLCN7 mutation. Am J Med Genet A, 170 (11), pp. 2988-2992. | Show Abstract | Read more
  • Lek M, Karczewski KJ, Minikel EV, Samocha KE, Banks E, Fennell T, O'Donnell-Luria AH, Ware JS, Hill AJ, Cummings BB et al. 2016. Analysis of protein-coding genetic variation in 60,706 humans. Nature, 536 (7616), pp. 285-291. | Citations: 50 (Scopus) | Show Abstract | Read more
  • Walsh R, Thomson KL, Ware JS, Funke BH, Woodley J, McGuire KJ, Mazzarotto F, Blair E, Seller A, Taylor JC et al. 2016. Reassessment of Mendelian gene pathogenicity using 7,855 cardiomyopathy cases and 60,706 reference samples. Genet Med, | Show Abstract | Read more
  • Cuella-Martin R, Oliveira C, Lockstone HE, Snellenberg S, Grolmusova N, Chapman JR. 2016. 53BP1 Integrates DNA Repair and p53-Dependent Cell Fate Decisions via Distinct Mechanisms. Mol Cell, 64 (1), pp. 51-64. | Show Abstract | Read more
  • Miles A, Iqbal Z, Vauterin P, Pearson R, Campino S, Theron M, Gould K, Mead D, Drury E, O'Brien J et al. 2016. Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum. Genome Res, 26 (9), pp. 1288-1299. | Show Abstract | Read more
  • Schofield EC, Carver T, Achuthan P, Freire-Pritchett P, Spivakov M, Todd JA, Burren OS. 2016. CHiCP: a web-based tool for the integrative and interactive visualization of promoter capture Hi-C datasets. Bioinformatics, 32 (16), pp. 2511-2513. | Citations: 1 (Scopus) | Show Abstract | Read more
  • Gharahkhani P, Fitzgerald RC, Vaughan TL, Palles C, Gockel I, Tomlinson I, Buas MF, May A, Gerges C, Anders M et al. 2016. Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis. Lancet Oncol, 17 (10), pp. 1363-1373. | Citations: 1 (Scopus) | Show Abstract | Read more
  • Martinez-Garay I, Guidi LG, Holloway ZG, Bailey MA, Lyngholm D, Schneider T, Donnison T, Butt SJ, Monaco AP, Molnár Z, Velayos-Baeza A. 2016. Normal radial migration and lamination are maintained in dyslexia-susceptibility candidate gene homolog Kiaa0319 knockout mice. Brain Struct Funct, pp. 1-18. | Show Abstract | Read more
  • Miranda F, Mannion D, Liu S, Zheng Y, Mangala LS, Redondo C, Herrero-Gonzalez S, Xu R, Taylor C, Chedom DF et al. 2016. Salt-Inducible Kinase 2 Couples Ovarian Cancer Cell Metabolism with Survival at the Adipocyte-Rich Metastatic Niche. Cancer Cell, 30 (2), pp. 273-289. | Show Abstract | Read more
  • Shearer FM, Huang Z, Weiss DJ, Wiebe A, Gibson HS, Battle KE, Pigott DM, Brady OJ, Putaporntip C, Jongwutiwes S et al. 2016. Estimating Geographical Variation in the Risk of Zoonotic Plasmodium knowlesi Infection in Countries Eliminating Malaria. PLoS Negl Trop Dis, 10 (8), pp. e0004915. | Show Abstract | Read more
  • Buas MF, He Q, Johnson LG, Onstad L, Levine DM, Thrift AP, Gharahkhani P, Palles C, Lagergren J, Fitzgerald RC et al. 2016. Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma. Gut, pp. gutjnl-2016-311622-gutjnl-2016-311622. | Show Abstract | Read more
  • Afolabi MO, Tiono AB, Adetifa UJ, Yaro JB, Drammeh A, Nébié I, Bliss C, Hodgson SH, Anagnostou NA, Sanou GS et al. 2016. Safety and Immunogenicity of ChAd63 and MVA ME-TRAP in West African Children and Infants. Mol Ther, 24 (8), pp. 1470-1477. | Show Abstract | Read more
  • Carvajal-Carmona LG, Tomlinson I, Sahasrabudhe R. 2016. RE: HABP2 G534E Mutation in Familial Nonmedullary Thyroid Cancer. J Natl Cancer Inst, 108 (8), pp. djw108-djw108. | Read more
  • Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, Agarwala V, Gaulton KJ, Ma C, Fontanillas P, Moutsianas L, McCarthy DJ et al. 2016. The genetic architecture of type 2 diabetes. Nature, 536 (7614), pp. 41-47. | Citations: 12 (Scopus) | Show Abstract | Read more
  • Leedham SJ, Chetty R. 2016. Wnt disruption in colorectal polyps - the traditional serrated adenoma enters the fray. J Pathol, 239 (4), pp. 387-390. | Show Abstract | Read more
  • Findlay JM, Middleton MR, Tomlinson I. 2016. Genetic susceptibility to Barrett's oesophagus: Lessons from early studies. United European Gastroenterol J, 4 (4), pp. 485-492. | Show Abstract | Read more
  • Rollier CS, Hill AV, Reyes-Sandoval A. 2016. Influence of adenovirus and MVA vaccines on the breadth and hierarchy of T cell responses. Vaccine, 34 (38), pp. 4470-4474. | Show Abstract | Read more
  • Auburn S, Serre D, Pearson RD, Amato R, Sriprawat K, To S, Handayuni I, Suwanarusk R, Russell B, Drury E et al. 2016. Genomic Analysis Reveals a Common Breakpoint in Amplifications of the Plasmodium vivax Multidrug Resistance 1 Locus in Thailand. J Infect Dis, 214 (8), pp. 1235-1242. | Show Abstract | Read more
  • Domingo E, Freeman-Mills L, Rayner E, Glaire M, Briggs S, Vermeulen L, Fessler E, Medema JP, Boot A, Morreau H et al. 2016. Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study The Lancet Gastroenterology & Hepatology, 1 (3), pp. 207-216. | Show Abstract | Read more
  • Pigott DM, Millear AI, Earl L, Morozoff C, Han BA, Shearer FM, Weiss DJ, Brady OJ, Kraemer MU, Moyes CL et al. 2016. Updates to the zoonotic niche map of Ebola virus disease in Africa. Elife, 5 (2016JULY), | Show Abstract | Read more
  • Walford GA, Gustafsson S, Rybin D, Stančáková A, Chen H, Liu CT, Hong J, Jensen RA, Rice K, Morris AP et al. 2016. Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci. Diabetes, 65 (10), pp. 3200-3211. | Show Abstract | Read more
  • Wyszynski A, Hong CC, Lam K, Michailidou K, Lytle C, Yao S, Zhang Y, Bolla MK, Wang Q, Dennis J et al. 2016. An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression. Hum Mol Genet, pp. ddw223-ddw223. | Show Abstract | Read more
  • Thomson E, Ip CL, Badhan A, Christiansen MT, Adamson W, Ansari MA, Bibby D, Breuer J, Brown A, Bowden R et al. 2016. Comparison of Next-Generation Sequencing Technologies for Comprehensive Assessment of Full-Length Hepatitis C Viral Genomes. J Clin Microbiol, 54 (10), pp. 2470-2484. | Show Abstract | Read more
  • Balestrini S, Milh M, Castiglioni C, Lüthy K, Finelli MJ, Verstreken P, Cardon A, Stražišar BG, Holder JL, Lesca G et al. 2016. TBC1D24 genotype-phenotype correlation: Epilepsies and other neurologic features. Neurology, 87 (1), pp. 77-85. | Citations: 1 (Scopus) | Show Abstract | Read more
  • Hellner K, Miranda F, Fotso Chedom D, Herrero-Gonzalez S, Hayden DM, Tearle R, Artibani M, KaramiNejadRanjbar M, Williams R, Gaitskell K et al. 2016. Premalignant SOX2 overexpression in the fallopian tubes of ovarian cancer patients: Discovery and validation studies. EBioMedicine, 10 pp. 137-149. | Show Abstract | Read more
  • Sharp K, Kretzschmar W, Delaneau O, Marchini J. 2016. Phasing for medical sequencing using rare variants and large haplotype reference panels. Bioinformatics, 32 (13), pp. 1974-1980. | Show Abstract | Read more
  • Crosnier C, Iqbal Z, Knuepfer E, Maciuca S, Perrin AJ, Kamuyu G, Goulding D, Bustamante LY, Miles A, Moore SC et al. 2016. Binding of Plasmodium falciparum Merozoite Surface Proteins DBLMSP and DBLMSP2 to Human Immunoglobulin M Is Conserved among Broadly Diverged Sequence Variants. J Biol Chem, 291 (27), pp. 14285-14299. | Show Abstract | Read more
  • Choi K, Reinhard C, Serra H, Ziolkowski PA, Underwood CJ, Zhao X, Hardcastle TJ, Yelina NE, Griffin C, Jackson M et al. 2016. Recombination Rate Heterogeneity within Arabidopsis Disease Resistance Genes. PLoS Genet, 12 (7), pp. e1006179. | Show Abstract | Read more
  • Zondervan KT, Rahmioglu N, Morris AP, Nyholt DR, Montgomery GW, Becker CM, Missmer SA. 2016. Beyond Endometriosis Genome-Wide Association Study: From Genomics to Phenomics to the Patient. Semin Reprod Med, 34 (4), pp. 242-254. | Show Abstract | Read more
  • Rogers PA, Adamson GD, Al-Jefout M, Becker CM, D'Hooghe TM, Dunselman GA, Fazleabas A, Giudice LC, Horne AW, Hull ML et al. 2016. Research Priorities for Endometriosis: Recommendations From a Global Consortium of Investigators in Endometriosis. Reprod Sci, | Show Abstract | Read more
  • Pearson RD, Amato R, Auburn S, Miotto O, Almagro-Garcia J, Amaratunga C, Suon S, Mao S, Noviyanti R, Trimarsanto H et al. 2016. Genomic analysis of local variation and recent evolution in Plasmodium vivax. Nat Genet, 48 (8), pp. 959-964. | Citations: 8 (Scopus) | Show Abstract | Read more
  • Jarvis D, Mitchell JS, Law PJ, Palin K, Tuupanen S, Gylfe A, Hänninen UA, Cajuso T, Tanskanen T, Kondelin J et al. 2016. Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer. Br J Cancer, 115 (2), pp. 266-272. | Show Abstract | Read more
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